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L-Arginine and L-Citrulline in HoneyPezil: Four Names on Label A
Label A of HoneyPezil prints four amino acid lines: L-arginine 200 mg, L-arginine AKG 200 mg, L-citrulline HCl 100 mg and L-citrulline malate 100 mg, 600 mg together. They are not on Label B. Mayo Clinic lists arginine's side effects and interactions; we found no memory evidence.
Written by the HoneyPezil label deskUpdated
The names on the bottle01
What are L-arginine and L-citrulline in HoneyPezil?
L-arginine and L-citrulline are amino acids, and Label A prints four lines of them: two forms of arginine and two forms of citrulline, 600 mg in all.
Amino acids are the small pieces that make up proteins, and the body also uses some for other jobs. Arginine is used to make nitric oxide, a gas that relaxes blood vessel walls. Citrulline is turned into arginine by the kidneys. The "AKG" in the second line means arginine joined to alpha-ketoglutarate, and "malate" means citrulline joined to malic acid. "HCl" means a hydrochloride salt. Those are different ways to package the same amino acid.
| Name | Panel | Printed amount |
|---|---|---|
| L-Arginine (base) | Label A | 200 mg |
| L-Arginine AKG 2:1 Extract | Label A | 200 mg |
| L-Citrulline HCl | Label A | 100 mg |
| L-Citrulline Malate | Label A | 100 mg |
These four lines appear on Label A only. If your bottle prints Label B, none of them are in it.
What sources say02
What does the evidence say about arginine and citrulline?
The sources we read describe arginine's safety and interactions but not a memory benefit, and for citrulline we found no verified source.
Mayo Clinic says oral L-arginine is generally considered safe, lists side effects such as nausea, abdominal pain, diarrhea, bloating, gout, allergic reactions and worsened asthma, and says it is not recommended after a recent heart attack 1. It also lists interactions with blood-pressure medicines, diabetes medicines and nitrates. None of that is a claim about memory.
For citrulline in both forms, we found no verified source we could cite, so we say that and stop. The sales page lists the four lines by name with no amounts and cites no study 2.
The body turns citrulline into arginine, and arginine feeds nitric oxide. That is basic biology. It is not a trial showing that a capsule with these names helps memory.
The amounts03
How much arginine and citrulline is in a HoneyPezil capsule?
One capsule prints 400 mg of arginine (two forms) and 200 mg of citrulline (two forms), according to Label A.
| Line | Printed amount | What it is |
|---|---|---|
| L-Arginine (base) | 200 mg | The plain amino acid |
| L-Arginine AKG 2:1 Extract | 200 mg | Arginine with alpha-ketoglutarate, 2 to 1 |
| L-Citrulline HCl | 100 mg | Citrulline as a hydrochloride |
| L-Citrulline Malate | 100 mg | Citrulline with malic acid |
Because the label prints amounts, there is no hidden blend. But the "2:1" in the arginine AKG line means the 200 mg is the extract, not 200 mg of pure arginine, so how much arginine itself is inside is not printed. We do not add the two arginine lines together as pure arginine for that reason.
In the body04
What do arginine and citrulline do in the body?
In the body, citrulline is converted to arginine, and arginine is used to make proteins, urea and nitric oxide, a signaling gas that relaxes blood vessel walls.
That chain explains why the two names appear together on supplement labels. It does not explain a memory effect, which would need a trial in people. The honest summary is that the four lines are ordinary amino acids, packaged in different forms, at amounts printed per capsule.
Arginine
Used to make nitric oxide. Mayo Clinic lists side effects and interactions 1.
Citrulline
Converted to arginine. We found no verified source to cite.
The "carriers"
AKG, malate and HCl are partners that let the amino acid be sold as a stable powder.
Why four lines instead of two? The label does not say. One reading is that each pairing has its own marketing story. Another is that the formula is built to list many names. We cannot know, and we do not claim to.
HoneyPezil: from $49 a bottle30 capsules · 2, 3 or 6 bottles · free US shipping on 3 and 6 · 60-day money-back guarantee
See packsQuestions for the seller05
What should you ask the seller about the arginine and citrulline lines?
Ask the order desk three plain questions: how much pure arginine is in the 2:1 extract, which panel is on the bottle, and what study the seller relies on.
How much pure arginine?
The 2:1 extract line prints 200 mg of extract, not 200 mg of arginine. Ask what the arginine share is.
Which panel?
Label A has these four lines and Label B has none. The answer tells you whether these four lines are in your bottle at all.
Which study?
The sales page cites no study as readable text 2. Ask for the one the seller means.
Write the answers down with the date. If the seller sends a study, check that it tested these amino acids, at about these amounts, for memory, in people like you. A study of athletes taking grams is a study of athletes taking grams. A good answer is one you can check yourself. The batch page shows how to ask for a lab report for your lot, which would at least tell you whether the milligrams on the panel are what is in the capsule.
Care first06
Who should be careful with arginine?
People who take blood-pressure, diabetes or nitrate medicines, have had a recent heart attack, or have asthma should ask a doctor or pharmacist before taking arginine.
- Recent heart attack: Mayo Clinic says arginine is not recommended 1.
- Blood-pressure and diabetes medicines: interactions are listed; ask your pharmacist.
- Asthma: arginine may worsen it, per Mayo Clinic.
- Gout: arginine is listed with gout as a possible effect.
Keep taking prescribed medicine. Sudden confusion, trouble speaking or face, arm or leg weakness means 911. See the supplements and medicines guide for what to say to a pharmacist, and side effects for the full table. If you are a caregiver, take the bottle and the photo of its panel to the pharmacy yourself, so the pharmacist can read the real names instead of a description. Ask the pharmacist to write the names down for your records, and ask whether any of them should be avoided with the person's other medicines. A few minutes at the counter is worth more than an hour online.
FAQ07
Arginine and citrulline questions
What is L-arginine AKG 2:1?
Arginine joined to alpha-ketoglutarate in a 2 to 1 ratio. The 200 mg on Label A is the extract, so the pure arginine inside is not printed.
Is L-citrulline malate the same as L-citrulline HCl?
Both give citrulline; one is joined to malic acid and the other is a hydrochloride. Label A prints both at 100 mg.
Does arginine improve memory?
No source we read says so. Mayo Clinic lists its safety and interactions, not a memory benefit.
Is arginine safe with blood-pressure medicine?
Mayo Clinic lists an interaction. Ask your pharmacist before combining them.
Is there a study on citrulline for memory?
We found no verified source to cite, so we make no claim about it.
Are arginine and citrulline on Label B?
No. Label B lists glucosamine, ginkgo, turmeric, marigold, green tea and bamboo silica.
Who wrote this08
Written and reviewed by
Pages built from the label, the sales page and linked NIH, FDA, CDC, FTC and peer-reviewed sources.
Last updated . Read our editorial standards and how we check reviews. This website is the information site for a USA Authorized HoneyPezil Retailer. It is not the manufacturer or the distributor named on the label. We earn money when you buy through our order links.
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